{"title":"PICOglue Labeling Service","description":"","products":[{"product_id":"pico-antibody-labeling-service","title":"PICO Antibody Labeling Service","description":"\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe offer a\u003cstrong\u003e \u003c\/strong\u003e\u003c\/span\u003eprofessional service for labeling antibodies of your choice with PICOglue Labels\u003cspan style=\"font-weight: 400;\"\u003e, providing a highly sensitive and specific probe for various PICO applications. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOur service uses the \u003c\/span\u003e\u003cb\u003ePICOglue Labeling Technology\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e to ensure the superior quality and reliability of the labeled antibodies. We guarantee at least 75% labeling efficiency (many times close to 100%), with a labeled antibody stability of at least 12 months. The yield is high and the amount of labeled antibodies are enough for thousands of PICO assays. The expected concentration of the labeled antibody is in the range of 5 \u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e×\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e e\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e10 \u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e- 5 \u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e×\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e e\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e12\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e cp\/µL (copies per microliter).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cstrong\u003eContact us\u003c\/strong\u003e below for a quote!\u003c\/span\u003e\u003c\/p\u003e","brand":"PICO BioScience","offers":[{"title":"Default Title","offer_id":44415585124620,"sku":"RDS-000130","price":2000.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0042\/1026\/2051\/files\/Asset4.png?v=1683539215"},{"product_id":"pico-custom-assay-development","title":"PICO Custom Assay Development Service","description":"\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eActome offers a \u003c\/span\u003eprofessional service to design and perform your personalized PICO assays.\u003cspan style=\"font-weight: 400;\"\u003e With PICO you can detect and quantify \u003c\/span\u003e\u003cb\u003eindividual proteins, protein interactions, and post-translational modifications\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e with ultra-high sensitivity\u003c\/span\u003e in any liquid biological sample\u003cspan style=\"font-weight: 400;\"\u003e, such as cell lysates, cell extracts, serum, supernatant, or in vitro cell-free conditions.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe service includes the following major steps:\u003c\/span\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\n\u003cb\u003eSelection of Suitable Antibodies:\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e Our team of experts will work with you to identify the most appropriate antibodies for your PICO assay, taking into consideration the target antigen and the intended application.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\n\u003cb\u003eConjugation of PICOglue Labels to Your Antibody:\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e The PICOglue Labels are conjugated to the antibody using the PICOglue antibody labeling technology.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\n\u003cb\u003eQuality Control of the PICOglue-labeled antibody:\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e The PICOglue-labeled antibody is assessed for \u003c\/span\u003elabeling efficiency\u003cspan style=\"font-weight: 400;\"\u003e using Agilent's 2100 Bioanalyzer System to ensure that it meets the highest standards of accuracy and reliability. In addition \u003c\/span\u003ethe antibody concentration\u003cspan style=\"font-weight: 400;\"\u003e (labeled antibody molecules\/µL) is also determined using dPCR. \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\n\u003cb\u003ePICO Assay and dPCR Run:\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e The biological sample is lysed and mixed with the PICOglue-labeled antibodies. After the incubation period the dPCR readout is performed using QIAGEN's QIAcuity dPCR System.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\n\u003cb\u003eData Analysis:\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e After the dPCR run AMULATOR, our web-based analysis software, performs all the mathematical and statistical evaluation to calculate precise molar concentrations of your target molecule.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\n\u003cb\u003eReporting:\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e Our experts provide a detailed report of the results of your PICO assay including the \u003c\/span\u003eabsolute concentration of your target molecule (in molar concentration)\u003cspan style=\"font-weight: 400;\"\u003e, graphical representation of the data (box plots), and a step-by-step description of the entire experimental workflow.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cstrong\u003eContact us\u003c\/strong\u003e below for a quote!\u003c\/span\u003e\u003c\/p\u003e","brand":"PICO BioScience","offers":[{"title":"Default Title","offer_id":44422336577804,"sku":"RDS-000040","price":25000.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0042\/1026\/2051\/files\/Veritcalarrowwithbox.png?v=1683553244"},{"product_id":"pico-antibody-quality-control","title":"PICO Antibody Quality Control Service","description":"\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eActome offers a \u003c\/span\u003e\u003cb\u003eprofessional service to perform the quality control of your PICOglue-labeled antibodies\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe initial step of the PICO workflow is the labeling of your antibodies with PICO specific unique DNA oligonucleotides (PICOglue Labels). To ensure the antibodies are efficiently and accurately labeled with the PICOglue Labels a quality control step is included in the workflow. We use \u003c\/span\u003e\u003cb\u003eAgilent's Bioanalyzer, \u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003ea high resolution automated electrophoresis instrument, to determine the \u003c\/span\u003e\u003cb\u003elabeling efficiency of the antibody\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e and ensure that a sufficient amount of antibodies are conjugated with PICOglue Labels. In addition we also determine the \u003c\/span\u003e\u003cb\u003econcentration of the PICOglue-labeled antibodies \u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e(labeled antibody molecules\/µL) using dPCR and our PICO Amplification Core Kit with matching PICO Probes.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cspan style=\"font-weight: 400;\"\u003eTo take advantage of this service, all we need is a small amount of your PICOglue-labeled antibody (~3 µL) as input material.  We will perform the necessary quality control analysis to ensure the reliability of your PICOglue-labeled antibodies, allowing you to confidently use them in your PICO assays. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eGet in touch\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e below for a quote today.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"PICO BioScience","offers":[{"title":"Default Title","offer_id":44437632286988,"sku":"RDS-000140","price":900.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0042\/1026\/2051\/files\/AntibodyQC.png?v=1684140939"},{"product_id":"pico-antibody-selection-and-purchase-service","title":"PICO Antibody Selection and Purchase Service","description":"\u003cp\u003e\u003cspan\u003eSelection and purchase of an antibody for the PICOglue Antibody Labeling Service. \u003c\/span\u003e\u003c\/p\u003e","brand":"PICO BioScience","offers":[{"title":"Default Title","offer_id":49359910535436,"sku":"RDS-000180","price":873.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0042\/1026\/2051\/files\/Antibody-01.png?v=1727160739"}],"url":"https:\/\/pico-bioscience.myshopify.com\/collections\/pico-services.oembed","provider":"PICO BioScience GmbH","version":"1.0","type":"link"}